Skip to content

75+ Cancer Screener (75+CS)

SCREENING FOR BREAST, COLORECTAL AND PROSTATE CANCER IN 75+ YEARS OLD PATIENTS (also applicable for 65+)
Screening should be repeated annually.
Discipline of Geriatrics and Gerontology, Department of Medicine. Paulista School of Medicine (EPM), Federal University of São Paulo (UNIFESP). São Paulo, Brazil.
Authors: Marianne Wolff Rezende Teixeira, MD (UNIFESP); Matheus de Oliveira Barros, MD (UNIFESP); Gisele Wally Braga Colleoni, MD, PhD (UNIFESP)
Contributors: Maísa Braga Aguiar, MD (UNIFESP); Lia Alexandre Botelho de Paula, MD (UNIFESP); Luciano Pereira Soares, PhD (Insper); Adriana Bruscato Bortoluzzo, PhD (Insper); Ana Beatriz Galhardi Di Tommaso, MD, MSc (UNIFESP); Eduardo Canteiro Cruz, MD (UNIFESP); Maysa Seabra Cendoroglo, MD, PhD (UNIFESP)
Fluxograma de rastreio

Step of 5

CFS: FRIED: Dementia: 10-year mortality risk: Consent:
We do not store any data. Prognostic tools support, never replace, clinical judgment.
References
  1. Bach PB. Late-Stage Cancer End Points to Speed Cancer Screening Clinical Trials—Not So Fast. JAMA. 2024;331(22):1894-1895. doi: 10.1001/jama.2024.5821. PMID: 38583869.
  2. Brotzman LE, Zikmund-Fisher BJ. Perceived Barriers Among Clinicians and Older Adults Aged 65 and Older Regarding Use of Life Expectancy to Inform Cancer Screening: A Narrative Review and Comparison. Med Care Res Rev. 2023;80(4):372-385. doi: 10.1177/10775587231153269. PMID: 36800914; PMCID: PMC10716687.
  3. Cinar D, Tas D. Cancer in the elderly. North Clin Istanb. 2015;2(1):73-80. doi: 10.14744/nci.2015.72691. PMID: 28058345; PMCID: PMC5175057.
  4. Cruz M, Covinsky K, Widera EW, Stijacic-Cenzer I, Lee SJ. Predicting 10-year mortality for older adults. JAMA. 2013;309(9):874-876. doi: 10.1001/jama.2013.1184. PMID: 23462780; PMCID: PMC3760279.
  5. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, Schneider SM, Sieber CC, Topinkova E, Vandewoude M, Visser M, Zamboni M; Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. doi: 10.1093/ageing/afy169. Erratum in: Age Ageing. 2019;48(4):601. doi: 10.1093/ageing/afz046. PMID: 30312372; PMCID: PMC6322506.
  6. Deardorff WJ, Barnes DE, Jeon SY, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Whitlock EL, Smith AK, Lee SJ. Development and External Validation of a Mortality Prediction Model for Community-Dwelling Older Adults With Dementia. JAMA Intern Med. 2022;182(11):1161-1170. doi: 10.1001/jamainternmed.2022.4326. PMID: 36156062; PMCID: PMC9513707.
  7. Francisco PMSB, et al. Prevalência de diagnóstico e tipos de câncer em idosos: dados da Pesquisa Nacional de Saúde 2013. Rev Bras Geriatr Gerontol. 2020;23(2):e200023. doi: 10.1590/1981-22562020023.200023.
  8. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA; Cardiovascular Health Study Collaborative Research Group. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146–M156. doi: 10.1093/gerona/56.3.m146. PMID: 11253156.
  9. INSTITUTO NACIONAL DE CÂNCER (INCA). Estimativa 2023: incidência de câncer no Brasil. 2022. Disponível em: inca.gov.br.
  10. INCA. Detecção precoce do câncer. 2021. Disponível em: PDF.
  11. Kotwal AA, Walter LC. Cancer Screening in Older Adults: Individualized Decision-Making and Communication Strategies. Med Clin North Am. 2020;104(6):989-1006. doi: 10.1016/j.mcna.2020.08.002. PMCID: PMC7594102.
  12. Lee SJ, Lindquist K, Segal MR, Covinsky KE. Development and validation of a prognostic index for 4-year mortality in older adults. JAMA. 2006;295(7):801-808. doi: 10.1001/jama.295.7.801.
  13. Lee SJ, Boscardin WJ, Kirby KA, Covinsky KE. Individualizing life expectancy estimates for older adults using the Gompertz Law of Human Mortality. PLoS One. 2014;9(9):e108540. doi: 10.1371/journal.pone.0108540.
  14. Lee SJ, Boscardin WJ, Stijacic-Cenzer I, Conell-Price J, O'Brien S, Walter LC. Time lag to benefit after screening for breast and colorectal cancer: meta-analysis. BMJ. 2013;346:e8441. doi: 10.1136/bmj.e8441.
  15. Pereira LFF, et al. Lung cancer screening in Brazil: recommendations from Brazilian societies. J Bras Pneumol. 2024;50(1):e20230233. doi: 10.36416/1806-3756/e20230233. PMCID: PMC11095927.
  16. Pilleron S, Sarfati D, Janssen-Heijnen M, et al. Global cancer incidence in older adults, 2012 and 2035. Int J Cancer. 2019;144(1):49-58. doi: 10.1002/ijc.31664.
  17. Qaseem A, Harrod CS, Crandall CJ, Wilt TJ; ACP. Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults: Guidance Statement. Ann Intern Med. 2023;176(8):1092-1100. doi: 10.7326/M23-0779.
  18. Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, Mitnitski A. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005;173(5):489–495. doi: 10.1503/cmaj.050051. PMID: 16129869; PMCID: PMC1188185.
  19. Schoenborn NL, Massare J, Park R, et al. Assessment of Clinician Decision-making on Cancer Screening Cessation in Older Adults With Limited Life Expectancy. JAMA Netw Open. 2020;3(6):e206772. doi: 10.1001/jamanetworkopen.2020.6772.
  20. Schoenborn NL, Lee K, Pollack CE, et al. Older Adults' Views and Communication Preferences About Cancer Screening Cessation. JAMA Intern Med. 2017;177(8):1121-1128. doi: 10.1001/jamainternmed.2017.1778.
  21. Schoenborn NL, Bowman TL 2nd, Cayea D, et al. Primary Care Practitioners' Views on Incorporating Long-term Prognosis. JAMA Intern Med. 2016;176(5):671-678. doi: 10.1001/jamainternmed.2016.0670.
  22. Schonberg MA, Davis RB, McCarthy EP, Marcantonio ER. External validation of an index to predict up to 9-year mortality. J Am Geriatr Soc. 2011;59(8):1444-1451. doi: 10.1111/j.1532-5415.2011.03523.x.
  23. Schonberg MA, Davis RB, McCarthy EP, Marcantonio ER. Index to predict 5-year mortality of community-dwelling adults aged 65+. J Gen Intern Med. 2009;24(10):1115-1122. doi: 10.1007/s11606-009-1073-y.
  24. Shear MD, et al. Biden Is Diagnosed With an Aggressive Form of Prostate Cancer. New York Times. 18 maio 2025. Disponível em: nytimes.com.
  25. Smith RA, Andrews KS, Brooks D, et al. Cancer screening in the United States, 2019. CA Cancer J Clin. 2019;69(3):184-210. doi: 10.3322/caac.21557.
  26. SBU; SBOC; SBRT. Posicionamento sobre o rastreamento do câncer de próstata. 2023. Disponível em: portaldaurologia.org.br (PDF).
  27. Soung MC. Screening for cancer: when to stop? Med Clin North Am. 2015;99(2):249-262. doi: 10.1016/j.mcna.2014.11.002.
  28. Urban LABD, et al. Recomendações para o rastreamento do câncer de mama no Brasil. Radiol Bras. 2023;56(4):207–214. doi: 10.1590/0100-3984.2023.0064.
  29. USPSTF. Screening for Breast Cancer: Recommendation Statement. JAMA. 2024;331(22):1918-1930. doi: 10.1001/jama.2024.5534.
  30. USPSTF. Screening for Colorectal Cancer: Recommendation Statement. JAMA. 2021;325(10):1965-1977. doi: 10.1001/jama.2021.6238.
  31. USPSTF. Screening for Lung Cancer: Recommendation Statement. JAMA. 2021;325(10):962-970. doi: 10.1001/jama.2021.1117.
  32. USPSTF. Screening for Prostate Cancer: Recommendation Statement. JAMA. 2018;319(18):1901-1913. doi: 10.1001/jama.2018.3710.
  33. Vieira L, et al. Cancer no idoso: reflexões sobre o ônus da idade. Arq Catarinenses Med. 2022;50(3):123–132. doi: 10.63845/xk6p4574.
  34. Walter LC, Covinsky KE. Cancer screening in elderly patients: a framework for individualized decision making. JAMA. 2001;285(21):2750-2756. doi: 10.1001/jama.285.21.2750.
  35. Xu J, Liao J, Yan Q, et al. Trends analysis of cancer incidence, mortality, and survival for the elderly in the United States, 1975–2020. Cancer Med. 2024;13(15):e70062. doi: 10.1002/cam4.70062.
  36. Zhang Y, et al. What Should I Know About Stopping Routine Cancer Screening? JAMA Intern Med. 2023. Disponível em: jamanetwork.com.